Exosome and growth-factor microneedling
Treatments for skin quality, texture and firmness, delivered as a course rather than a single session. Modest, gradual change — not a substitute for surgery.
What the treatment is
Exosomes and growth factors are applied in combination with microneedling, which creates controlled micro-channels so the material reaches the layer where it can act. The intention is to support collagen production and improve skin texture and tone over a course of sessions.
The change is real but modest. If you are expecting the result of a surgical lift, this is not that, and we would rather say so now than after you have paid.


Images and case example above are supplied by AGF Mesenchymal, the manufacturer of AGF Mesenchymal Dermal, from their own marketing and evidence materials. They are not photographs of Regenesis BioAdvanced patients unless stated otherwise, and results shown are the manufacturer's selected examples rather than a guarantee of what any individual patient will experience.
Who it helps
- Fine lines and early loss of firmness
- Uneven texture and enlarged pores
- Dullness and uneven tone
- Some acne scarring
- Patients wanting maintenance rather than dramatic change
- Those looking to support results after other aesthetic procedures
Where this stops working
Who it will not help
Active skin infection or inflammatory skin disease at the treatment site, keloid tendency, recent isotretinoin use, and pregnancy.
We also decline where expectations remain unrealistic after discussion. If what you want is the outcome of a facelift, nothing offered here will deliver it, and beginning a course on that basis ends badly for both of us.
The protocol
Confirmed by the physician after reviewing your case, and fixed once you have been quoted. If the plan changes, the price does not change without your agreement.
Priced per course. Single sessions are available but the published course price assumes the full protocol, which is what the evidence for this treatment is based on.
- LocationAesthetic Spa, P.º del Centenario 9580, Tijuana
- Material usedAGF Mesenchymal Dermal — topical exosomes and growth factors
- Delivered byMicroneedling
- Manufacturer's published example resultVisible improvement in skin texture and firmness reported after 5 sessions in the maker's own case documentation — case-dependent, not a guarantee
- Your protocolNumber of sessions and interval confirmed by the physician after your case review
What to expect
Most patients notice improved texture and tone within weeks of the second or third session. Firmness changes, where they occur, develop over months as collagen remodels.
Results fade. This is maintenance, and the interval between courses is discussed as part of the plan.
- The result of a surgical lift
- Removal of deep folds or significant laxity
- Permanent results
- A specific number of years off your appearance
- Identical outcomes to anyone else's before-and-after
Questions about this programme
Microneedling is uncomfortable rather than painful, and topical anaesthetic is used. Most patients describe the sensation as tolerable and brief.
Often yes, but sequencing matters and should be planned with the physician rather than improvised across two clinics.
We will publish them once we have patient consent and images taken under consistent lighting and angles. Side-by-side comparisons shot under different conditions are misleading, and we would rather show nothing than show that.
This programme is delivered at our Aesthetic Spa, P.º del Centenario 9580, Zona Urbana Rio Tijuana, Tijuana.
Before you decide, read
- September 2026 · 2 minCrossing at San Ysidro for a medical appointmentThe practical detail nobody publishes: documents, timing, what the queue is actually like, and how to plan a same-day appointment from San Diego.Read the article
- September 2026 · 2 minStem cells and exosomes are not the same thingThe two are used almost interchangeably in clinic marketing. They are different products, with different costs and different reasons to choose one over the other.Read the article
- September 2026 · 2 minTwelve questions to ask a stem cell clinic before you bookYou are about to travel to another country and pay out of pocket for a treatment your insurer will not cover. These are the questions that separate a serious clinic from a confident one.Read the article
Other programmes
- Orthopedic & joint regenerationTargeted injections for knee, hip and back pain, osteoarthritis, cartilage wear and sports injuries — a non-surgical option for patients weighing joint replacement.
- Hair regrowth & restorationScalp treatment using exosomes and growth factors for androgenetic alopecia and thinning, in men and women, without surgery.
- Sexual health & vitalityRegenerative protocols for erectile dysfunction and intimate rejuvenation, following a workup that establishes what is actually causing the problem.
- Systemic wellness & IV therapyIntravenous stem cell and exosome protocols intended to support recovery, immune function and inflammatory load across the body.
Find out whether we can help you
A few questions about your condition, reviewed by a physician at no cost. If regenerative therapy isn't right for your case, we will tell you that instead of selling you something.
Start the case reviewA physician replies within two working days. No obligation, no payment at this stage.