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RegenesisBioAdvanced
ProgrammesOrthopedic & joint regeneration

Stem cell therapy for knees, hips and back

Injections placed directly into the affected joint, for osteoarthritis, cartilage wear and sports injuries. A non-surgical option for patients who have been told the next step is replacement.

What the treatment is

Mesenchymal cells and exosomes are injected under guidance into the affected joint. The intention is to reduce the inflammatory activity driving the pain and to support the tissue that remains, rather than to grow a new joint surface.

That distinction matters. This is not a replacement for cartilage that has already gone, and any clinic describing it that way is overstating what the procedure does.

How the injection is placed

Two bones, a cartilage cap on each surface, the meniscus wedges that cushion them, and the synovial fluid that fills the joint.

Who it helps

  • Knee osteoarthritis, mild to moderate
  • Hip osteoarthritis, mild to moderate
  • Chronic lower back pain of facet or disc origin
  • Rotator cuff and shoulder tendinopathy
  • Sports injuries: meniscus, ligament, tendon
  • Patients who want to postpone or avoid joint replacement

Where this stops working

Who it will not help

End-stage joint destruction, where imaging shows bone contacting bone with no remaining cartilage surface. At that point there is no viable matrix for injected cells to work within. Some patients report short-term pain relief, but the structure does not change, and joint replacement remains the intervention with real evidence behind it.

We also decline where there is active infection in the joint, active malignancy, or uncontrolled diabetes affecting healing.

See all exclusions

The protocol

Confirmed by the physician after reviewing your case, and fixed once you have been quoted. If the plan changes, the price does not change without your agreement.

Full protocol price is published on the pricing page. It does not vary by patient, and it includes the physician consultation, the protocol itself and follow-up at three, six and twelve months.

See full pricing

  • Ampoules per protocolTBC
  • Cells administeredTBC
  • Injection sessionsTBC
  • Visits to the clinicTBC
  • Time on site per visitTBC
  • GuidanceTBC
  • Recovery before normal activityTBC

What to expect

Most patients report improvement in pain and function within three to six months. Some require a repeat course. Some see no meaningful improvement at all.

Where response occurs, it tends to be gradual rather than immediate — this is not a cortisone injection, and if you feel nothing in the first fortnight that is expected rather than a sign of failure.

What we do not promise
  • Cartilage regrowth
  • That you will avoid joint replacement permanently
  • Return to competitive sport
  • A specific percentage of pain reduction
  • Any result at all in a joint that is already at end stage

Questions about this programme

No. Platelet-rich plasma is prepared from your own blood and delivers growth factors from your platelets. What we use is a cellular product from an external certified laboratory. PRP is a reasonable and cheaper option for some presentations, and where it is the better fit we will say so.

Your existing imaging will usually say. If you have an X-ray or MRI report, the grade is generally stated in it. Send it with your case review and the physician will tell you plainly where you sit and whether this is worth your time.

Usually yes. It affects the number of ampoules required, and therefore the price — the physician will confirm this before you travel.

We schedule follow-up at three, six and twelve months regardless of outcome. If there has been no response we will tell you that rather than recommending another course by default. Nobody in this field offers refunds based on outcome, which is a further reason to be certain about your expectations first.

Find out whether we can help you

A few questions about your condition, reviewed by a physician at no cost. If regenerative therapy isn't right for your case, we will tell you that instead of selling you something.

Start the case review

A physician replies within two working days. No obligation, no payment at this stage.